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Nutropin AQ® NuSpin® Prefilled Pen

Designed to be as simple as 1, 2, 3

Nutropin AQ® NuSpin® comes prefilled and delivers treatment in 3 simple steps. See more user-friendly features below.

Nutropin AQ® NuSpin® offers a variety of dosing options to fit your needs:

Nutropin AQ® NuSpin® 5 logo
Nutropin AQ® NuSpin® 10 logo
Nutropin AQ® NuSpin® 20 logo

For more information about the Nutropin AQ® NuSpin®, review the user guide or watch the injection video.

How to Use NuSpin for Injections

For injection tips, click here.

Injection tips

If you or your child has pain while injecting Nutropin AQ, talk to your doctor. Some things that can make injections more comfortable include:

  1. Allow the Nutropin AQ to come to room temperature prior to injection. Once you are finished with the injection, remember to return the drug to the refrigerator.
  2. Be sure to inject Nutropin at a different recommended place on your body each time to avoid tissue breakdown. A doctor or nurse should provide injection training and supervise the first injection. Use the Nutropin AQ Monthly Tracker to help you keep track of injection sites and your dosing schedule.
  3. Relax your muscles in the injection area during injection.
  4. Sometimes the length of the needle may affect how it feels. It is important to discuss needle options with your healthcare professional, who will recommend a needle that is appropriate for you.
  5. Try putting ice on the injection site first to numb it.
  6. Make sure alcohol from the alcohol wipe has dried completely before injecting.
  7. Use a dry cotton pad instead of an alcohol pad on the injection site when you remove the needle.

Select Important Safety Information

Contact your doctor immediately if you experience any allergic reaction to the injection of Nutropin therapy.

Occasionally, a problem may develop at an injection site. Contact your healthcare professional if you notice any of the following:

  • A lump that doesn't go away
  • Bruising that doesn't go away
  • Any signs of infection or inflammation such as swelling, pus, persistent redness or pain, or skin that is hot to the touch

INDICATIONS:

WHO IS NUTROPIN THERAPY FOR?

Nutropin AQ® (somatropin) injection for subcutaneous use is a human growth hormone that is available by prescription only.
Doctors prescribe Nutropin therapy for children and teenagers who are short or growing slowly because they:

  • Do not make enough growth hormone on their own
  • Have idiopathic short stature, which means they are shorter than 98.8% of other children of the same age and sex; are growing at a rate not likely to allow them to reach normal adult height; and no other cause of short stature can be found
  • Have Turner syndrome
  • Have chronic kidney disease (CKD) up to the time of kidney transplant

Doctors prescribe Nutropin therapy for adults who have growth hormone deficiency that began either in:

  • Adulthood as a result of pituitary disease, diseases of the hypothalamus, surgery, radiation therapy, or trauma; or
  • Childhood. Patients treated for growth hormone deficiency in childhood, whose bones have stopped growing, should be reevaluated to see if they need to continue with growth hormone therapy

Your doctor will test to see if growth hormone is right for you.

IMPORTANT SAFETY INFORMATION

Nutropin therapy and your safety:

Please read this Important Safety Information carefully. Then, if you have any questions, talk with your doctor.

NUTROPIN THERAPY IS NOT FOR:

  • Patients having serious complications after undergoing open heart surgery, abdominal surgery, serious injuries involving many body systems, or life-threatening breathing problems. Deaths have been reported in such cases
  • Children who have Prader-Willi syndrome (PWS) and are very overweight or have a history of severe breathing problems. Deaths have been reported in children with PWS who are very overweight, have a history of blocked upper airways, sleep apnea (pauses in breathing during sleeping), or other severe breathing problems
  • Patients who have active cancer. Because growth hormone deficiency can be an early sign of some tumors in the brain or pituitary gland, the presence of these types of tumors should be ruled out by your doctor before you start Nutropin therapy
  • Patients who are allergic to somatropin, the active ingredient in Nutropin therapy, or the inactive ingredients in Nutropin therapy
  • Adults or children with certain types of eye disease caused by diabetes
  • Children and teenagers whose bones have finished growing

What should you tell your doctor before starting Nutropin therapy?

  • If you take cyclosporine, hormone replacement therapy, insulin or other diabetes medications, drugs containing steroids, or drugs for seizures. These medications may need to be adjusted during Nutropin therapy
  • If you had cancer as a child. An increased risk of a new tumor, particularly certain brain tumors, has been reported in patients taking Nutropin therapy. If you have pre-existing tumors or growth hormone deficiency caused by abnormal tissue in the brain, you should be watched closely for the worsening or return of this condition
  • If you have diabetes, risk factors for diabetes, or impaired glucose tolerance. If so, your doctor should monitor your blood sugar closely during Nutropin therapy. New cases of type 2 diabetes have been reported in patients taking Nutropin therapy
  • If you have pituitary hormone deficiency(s) (an inability of the pituitary gland to produce sufficient hormones) or adrenal hormone deficiency (an inability of the adrenal glands to produce sufficient hormones, primarily cortisol). Your doctor may further monitor your hormone levels or your hormone replacement therapy closely while you are taking Nutropin therapy
  • If you are pregnant, nursing, or plan to become pregnant. It is not known whether Nutropin is excreted in human milk. Nutropin therapy should be used during pregnancy only when clearly needed

While taking Nutropin, contact your doctor immediately if you experience:

  • Changes in upper airway obstruction (including onset of or increased snoring) and/or new onset sleep apnea, in patients with PWS. These patients should also have effective weight control and be monitored by a doctor for signs of respiratory infection
  • Changes in vision, a bad headache, or nausea with or without vomiting. This may be a sign of increased pressure in the brain
  • Any allergic reaction you experience to the injection of Nutropin therapy
  • A limp or have hip or knee pain
    • A fracture in the ball of the hip joint can occur in children who have endocrine problems and in children who have rapid growth
    • Children with growth failure due to CKD should be examined periodically for evidence of loss of bone minerals. Hip x-rays should be taken before starting Nutropin therapy in these children
  • Progression of scoliosis (curvature of the spine) that can occur in children who have rapid growth. Nutropin therapy has not been shown to increase the occurrence of this condition
  • Increases in laboratory test serum levels of inorganic phosphorus, alkaline phosphatase, parathyroid hormone (PTH), or IGF-1
  • Abdominal pain. Cases of pancreatitis (inflammation of the pancreas) have been reported rarely in children and adults receiving Nutropin therapy

Other important information about Nutropin

  • Adults may retain water during Nutropin therapy. This may be brief but may increase with higher doses of Nutropin therapy
  • Patients should have their thyroid function tested periodically during Nutropin therapy. Thyroid hormone treatment may need to be started or adjusted
  • Patients should be sure to inject Nutropin at a different recommended place on their body each time to avoid tissue breakdown. A doctor or nurse should provide injection training and supervise the first injection
  • The use of Nutropin therapy has not been studied in patients over 65 years of age. Elderly patients may be more sensitive to Nutropin therapy and may experience more side effects
  • Patients with Turner syndrome should be monitored closely by a doctor for ear infections and cardiovascular problems during Nutropin therapy

What are common possible side effects of Nutropin therapy?

Common side effects reported in adults and children taking Nutropin therapy include injection site reactions. Additional common side effects in adults include swelling, joint pain, and carpal tunnel syndrome.

You may report side effects to FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.

How should you store Nutropin?

Nutropin must be kept refrigerated (36° to 46°F [2° to 8°C]). Do not freeze. Cartridges and NuSpin pens must be used within 28 days of initial use. Throw away any unused Nutropin after 28 days of initial use. Before giving an injection, check the manufacturer’s expiration date on the cartridge or pen. Do not use if it has expired. Do not inject medication if the solution is cloudy.

Please see accompanying Nutropin full Prescribing Information for additional Important Safety Information.