How to Take Nutropin AQ® [somatropin (rDNA origin) injection]

Nutropin AQ NuSpin

NuSpin was designed to be simple. With NuSpin, you can get your dose, delivered with confidence.

Nutropin AQ NuSpin offers a variety of dosing options to fit your needs:

For more information about the Nutropin AQ NuSpin, review the user guide or watch the injection video.

NuSpin User Guide (English/Spanish) - Download PDF (3.6 MB) NuSpin 20 Instructions for Use - Download PDF (827 KB) NuSpin 10 Instructions for Use - Download PDF (1 MB) NuSpin 5 Instructions for Use - Download PDF (1 MB)

Nutropin AQ Pen

The Nutropin AQ Pen offers the convenience of prefilled cartridges in a sturdy, reusable pen.

Color-coded Nutropin AQ Pen is available in 20 mg and 10 mg

Use only the purple 20 mg Nutropin AQ cartridge with the Nutropin AQ Pen 20

Use only the yellow 10 mg Nutropin AQ cartridge with the Nutropin AQ Pen 10

Nutropin AQ Pen Features:

  • Cartridges prefilled with Nutropin AQ
  • One-step, dial-back dose knob: Clicks that can be heard and felt
  • Digital dose display: Remembers the last dose

For more information about the Nutropin AQ Pen, you can review the quick reference guide.

Nutropin AQ Quick Reference Guide - Download PDF (899 KB) Nutropin AQ Pen Instructions for Use - Download PDF (4.3 MB)

Injection tips

If you or your child has pain while injecting Nutropin AQ, talk to your doctor. Some things that can make injections more comfortable include:

1

Allow the Nutropin AQ to come to room temperature prior to injection. Once you are finished with the injection, remember to return the drug to the refrigerator.

2

Be sure to inject Nutropin at a different recommended place on your body each time to avoid tissue breakdown. A doctor or nurse should provide injection training and supervise the first injection. Use the Nutropin AQ Monthly Tracker to help you keep track of injection sites and your dosing schedule.

3

Relax your muscles in the injection area during injection.

4

Sometimes the length of the needle may affect how it feels. An 8-mm or longer needle may help get the medication deeper into the tissue. It is important to discuss needle options with your healthcare professional, who will recommend a needle that is appropriate for you.

5

Try putting ice on the injection site first to numb it.

6

Make sure alcohol from the alcohol wipe has dried completely before injecting.

7

Use a dry cotton pad instead of an alcohol pad on the injection site when you remove the needle.

Select Important Safety Information

Contact your doctor immediately if you experience any allergic reaction to the injection of Nutropin therapy.

Occasionally, a problem may develop at an injection site. Contact your healthcare professional if you notice any of the following:

  • A lump that doesn't go away
  • Bruising that doesn't go away
  • Any signs of infection or inflammation such as swelling, pus, persistent redness or pain, or skin that is hot to the touch

Who is Nutropin Therapy For?

Nutropin AQ [somatropin (rDNA origin) injection] is human growth hormone that is available by prescription only.

Doctors prescribe Nutropin therapy for children and teenagers who are short or growing slowly because they:

  • Do not make enough growth hormone on their own
  • Have idiopathic short stature, which means they are shorter than 98.8% of other children of the same age and sex; are growing at a rate not likely to allow them to reach normal adult height; and no other cause of short stature can be found
  • Have Turner syndrome
  • Have chronic kidney disease (CKD) up to the time of kidney transplant

Doctors prescribe Nutropin therapy for adults who have growth hormone deficiency that began either in:

  • Adulthood as a result of pituitary disease, diseases of the hypothalamus, surgery, radiation therapy, or trauma; or
  • Childhood. Patients treated for growth hormone deficiency in childhood, whose bones have stopped growing, should be reevaluated to see if they need to continue with growth hormone therapy

Your doctor will test to see if growth hormone is right for you

Important Safety Information

Nutropin therapy and your safety:

Please read this important safety information carefully. Then, if you have any questions, talk with your doctor.

Nutropin Therapy is Not For:

  • Patients having serious complications after undergoing open heart surgery, abdominal surgery, serious injuries involving many body systems, or life-threatening breathing problems. Deaths have been reported in such cases
  • Children who have Prader-Willi syndrome (PWS) and are very overweight or have a history of severe breathing problems. Deaths have been reported in children with PWS who are very overweight, have a history of blocked upper airways, sleep apnea (pauses in breathing during sleeping), or other severe breathing problems
  • Patients who have active cancer. Because growth hormone deficiency can be an early sign of some tumors in the brain or pituitary gland, the presence of these types of tumors should be ruled out by your doctor before you start Nutropin therapy
  • Adults or children with certain types of eye disease caused by diabetes
  • Children and teenagers whose bones have finished growing
  • Patients who are allergic to somatropin, the active ingredient in Nutropin therapy. Reactions at the injection site are the most common allergic reactions

What should you tell your doctor before starting Nutropin therapy?

  • If you take cyclosporine, hormone replacement therapy, insulin or other diabetes medications, drugs containing steroids, or drugs for seizures. These medications may need to be adjusted during Nutropin therapy
  • If you have preexisting tumors or growth hormone deficiency caused by abnormal tissue in the brain. If so, you should be watched closely for the worsening or return of this condition. If you had cancer as a child, an increased risk of a new tumor, particularly certain brain tumors, has been reported in patients taking Nutropin therapy
  • If you have diabetes, risk factors for diabetes, or impaired glucose tolerance. If so, your doctor should monitor your blood sugar closely during Nutropin therapy. New cases of type 2 diabetes have been reported in patients taking Nutropin therapy
  • If you have hypopituitarism (an inability of the pituitary gland to produce sufficient hormones) and are on standard hormone replacement therapy. In that case, your doctor should monitor your hormone replacement therapy closely while you are taking Nutropin therapy
  • If you are pregnant, nursing, or plan to become pregnant. It is not known whether Nutropin is excreted in human milk. Nutropin therapy should be used during pregnancy only when clearly needed

While taking Nutropin, contact your doctor immediately if you experience:

  • Changes in vision, a bad headache, or nausea with or without vomiting. This may be a sign of increased pressure in the brain
  • A limp or have hip or knee pain
    • A fracture in the ball of the hip joint can occur in children who have endocrine problems and in children who have rapid growth
    • Children with growth failure due to CKD should be examined periodically for evidence of loss of bone minerals. Hip X-rays should be taken before starting Nutropin therapy in these children
  • Progression of scoliosis (curvature of the spine) that can occur in children who have rapid growth. Nutropin therapy has not been shown to increase the occurrence of this condition
  • Any allergic reaction you experience to the injection of Nutropin therapy
  • Abdominal pain. Cases of pancreatitis (inflammation of the pancreas) have been reported rarely in children and adults receiving Nutropin therapy

Other important information about Nutropin:

  • Adults may retain water during Nutropin therapy. This may be brief but may increase with higher doses of Nutropin therapy
  • Patients should have their thyroid function tested periodically during Nutropin therapy. Thyroid hormone treatment may need to be started or adjusted
  • Patients should be sure to inject Nutropin at a different recommended place on their body each time to avoid tissue breakdown. A doctor or nurse should provide injection training and supervise the first injection
  • The use of Nutropin therapy has not been studied in patients over 65 years of age. Elderly patients may be more sensitive to Nutropin therapy and may experience more side effects
  • Patients with Turner syndrome should be monitored closely by a doctor for ear infections and cardiovascular problems during Nutropin therapy
  • Nutropin therapy may affect the body's ability to process two hormones, cortisol and cortisone, which can lead to a condition called hypoadrenalism (underactivity of the adrenal gland). In that case, glucocorticoid replacement therapy may need to be prescribed

What are common possible side effects of Nutropin therapy?

Common side effects reported in adults and children taking Nutropin therapy include injection site reactions. Additional common side effects in adults include swelling, joint pain, and carpal tunnel syndrome.

You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1-888-835-2555.

How should you store Nutropin?

Nutropin must be kept refrigerated (36° to 46°F [2° to 8°C]). Do not freeze. Cartridges and NuSpin pens must be used within 28 days of initial use. Throw away any unused Nutropin after 28 days of initial use. Before giving an injection, check the manufacturer's expiration date on the cartridge or pen. Do not use if it has expired. Do not inject medication if the solution is cloudy.

Your healthcare team is your first source of information about your therapy.

Please see the full Prescribing Information for additional important safety information.

The content available from this website is for informational purposes only. Individual results may vary.

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