Go to Healthcare Professional Site

Prescribing Information

Matching the treatment to the condition

Children, teenagers, and adults with certain conditions may benefit from treatment with Nutropin AQ [somatropin (rDNA origin) injection].

Children and teenagers

Seeing a doctor called a pediatric endocrinologist—an expert on how hormones work in young people—and getting tested may identify a medical reason behind slowed growth.

Doctors prescribe Nutropin therapy for children and teenagers who are short or growing slowly because they:

Adults

Your healthcare professional can test you to see if you have growth hormone (GH) deficiency. Doctors may prescribe Nutropin therapy for adults who have growth hormone deficiency that began either in:

  • Adulthood as a result of pituitary disease, diseases of the hypothalamus, surgery, radiation therapy, or trauma; or
  • Childhood. Patients treated for growth hormone deficiency in childhood, whose bones have stopped growing, should be reevaluated to see if they need to continue with growth hormone therapy (adult growth hormone deficiency)

WHO IS NUTROPIN THERAPY FOR?

Nutropin AQ [somatropin (rDNA origin) injection] is human growth hormone that is available by prescription only in a disposable pen called NuSpin.

Doctors prescribe Nutropin therapy for children and teenagers who are short or growing slowly because they:

  • Do not make enough growth hormone on their own
  • Have idiopathic short stature, which means they are shorter than 98.8% of other children of the same age and sex; are growing at a rate not likely to allow them to reach normal adult height; and no other cause of short stature can be found
  • Have Turner syndrome
  • Have chronic kidney disease (CKD) up to the time of kidney transplant

Doctors prescribe Nutropin therapy for adults who have growth hormone deficiency that began either in:

  • Adulthood as a result of pituitary disease, diseases of the hypothalamus, surgery, radiation therapy, or trauma; or
  • Childhood. Patients treated for growth hormone deficiency in childhood, whose bones have stopped growing, should be reevaluated to see if they need to continue with growth hormone therapy

Your doctor will test to see if growth hormone is right for you.

IMPORTANT SAFETY INFORMATION

Nutropin therapy and your safety:

Please read this important safety information carefully. Then, if you have any questions, talk with your doctor.

NUTROPIN THERAPY IS NOT FOR:

What should you tell your doctor before starting Nutropin therapy?

  • If you take cyclosporine, hormone replacement therapy, insulin or other diabetes medications, drugs containing steroids, or drugs for seizures. These medications may need to be adjusted during Nutropin therapy
  • If you have preexisting tumors or growth hormone deficiency caused by abnormal tissue in the brain. If so, you should be watched closely for the worsening or return of this condition. If you had cancer as a child, an increased risk of a new tumor, particularly certain brain tumors, has been reported in patients taking Nutropin therapy
  • If you have diabetes, risk factors for diabetes, or impaired glucose tolerance. If so, your doctor should monitor your blood sugar closely during Nutropin therapy. New cases of type 2 diabetes have been reported in patients taking Nutropin therapy
  • If you have hypopituitarism (an inability of the pituitary gland to produce sufficient hormones) and are on standard hormone replacement therapy. In that case, your doctor should monitor your hormone replacement therapy closely while you are taking Nutropin therapy
  • If you are pregnant, nursing, or plan to become pregnant. It is not known whether Nutropin is excreted in human milk. Nutropin therapy should be used during pregnancy only when clearly needed

While taking Nutropin, contact your doctor immediately if you experience:

  • Changes in vision, a bad headache, or nausea with or without vomiting. This may be a sign of increased pressure in the brain
  • A limp or have hip or knee pain
    • A fracture in the ball of the hip joint can occur in children who have endocrine problems and in children who have rapid growth
    • Children with growth failure due to CKD should be examined periodically for evidence of loss of bone minerals. Hip X-rays should be taken before starting Nutropin therapy in these children
  • Progression of scoliosis (curvature of the spine) that can occur in children who have rapid growth. Nutropin therapy has not been shown to increase the occurrence of this condition
  • Any allergic reaction you experience to the injection of Nutropin therapy
  • Abdominal pain. Cases of pancreatitis (inflammation of the pancreas) have been reported rarely in children and adults receiving Nutropin therapy

Other important information about Nutropin:

  • Adults may retain water during Nutropin therapy. This may be brief but may increase with higher doses of Nutropin therapy
  • Patients should have their thyroid function tested periodically during Nutropin therapy. Thyroid hormone treatment may need to be started or adjusted
  • Patients should be sure to inject Nutropin at a different recommended place on their body each time to avoid tissue breakdown. A doctor or nurse should provide injection training and supervise the first injection
  • The use of Nutropin therapy has not been studied in patients over 65 years of age. Elderly patients may be more sensitive to Nutropin therapy and may experience more side effects
  • Patients with Turner syndrome should be monitored closely by a doctor for ear infections and cardiovascular problems during Nutropin therapy
  • Nutropin therapy may affect the body's ability to process two hormones, cortisol and cortisone, which can lead to a condition called hypoadrenalism (underactivity of the adrenal gland). In that case, glucocorticoid replacement therapy may need to be prescribed

What are common possible side effects of Nutropin therapy?

Common side effects reported in adults and children taking Nutropin therapy include injection site reactions. Additional common side effects in adults include swelling, joint pain, and carpal tunnel syndrome.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How should you store Nutropin?

Nutropin must be kept refrigerated (36° to 46°F [2° to 8°C]). Do not freeze. Cartridges and NuSpin pens must be used within 28 days of initial use. Throw away any unused Nutropin after 28 days of initial use. Before giving an injection, check the manufacturer's expiration date on the cartridge or pen. Do not use if it has expired. Do not inject medication if the solution is cloudy.

Your doctor is your primary source of information about your therapy.

Please see the full Prescribing Information for Nutropin AQ, available from your pharmacy and at www.nutropin.com, for more about Nutropin and safety.

Questions? Call the Nurse Hotline at 1-866-NUTROPIN (1-866-688-7674).

Please see additional Important Safety Information below.

The content available from this website is for informational purposes only. Individual results may vary. You may report side effects to the FDA at 1-800-FDA-1088 or to Genentech Drug Safety/Adverse Events at 1-888-835-2555.

Nutropin AQ is a registered trademark and NuSpin, growingopportunity, and Nutropin GPS are trademarks of Genentech, Inc.

Back to top

Related Tools & Resources

My GH Story

HGH Story

Watch an inspiring real-life Human Growth Hormone journey.

Important Safety Information

WHO IS NUTROPIN THERAPY FOR?

Nutropin AQ [somatropin (rDNA origin) injection] is human growth hormone that is available by prescription only in a disposable pen called NuSpin.

Doctors prescribe Nutropin therapy for children and teenagers who are short or growing slowly because they:

  • Do not make enough growth hormone on their own
  • Have idiopathic short stature, which means they are shorter than 98.8% of other children of the same age and sex; are growing at a rate not likely to allow them to reach normal adult height; and no other cause of short stature can be found
  • Have Turner syndrome
  • Have chronic kidney disease (CKD) up to the time of kidney transplant

Doctors prescribe Nutropin therapy for adults who have growth hormone deficiency that began either in:

  • Adulthood as a result of pituitary disease, diseases of the hypothalamus, surgery, radiation therapy, or trauma; or
  • Childhood. Patients treated for growth hormone deficiency in childhood, whose bones have stopped growing, should be reevaluated to see if they need to continue with growth hormone therapy

Your doctor will test to see if growth hormone is right for you.

IMPORTANT SAFETY INFORMATION

Nutropin therapy and your safety:

Please read this important safety information carefully. Then, if you have any questions, talk with your doctor.

NUTROPIN THERAPY IS NOT FOR:

  • Patients having serious complications after undergoing open heart surgery, abdominal surgery, serious injuries involving many body systems, or life-threatening breathing problems. Deaths have been reported in such cases
  • Children who have Prader-Willi syndrome (PWS) and are very overweight or have a history of severe breathing problems. Deaths have been reported in children with PWS who are very overweight, have a history of blocked upper airways, sleep apnea (pauses in breathing during sleeping), or other severe breathing problems
  • Patients who have active cancer. Because growth hormone deficiency can be an early sign of some tumors in the brain or pituitary gland, the presence of these types of tumors should be ruled out by your doctor before you start Nutropin therapy
  • Adults or children with certain types of eye disease caused by diabetes
  • Children and teenagers whose bones have finished growing
  • Patients who are allergic to somatropin, the active ingredient in Nutropin therapy. Reactions at the injection site are the most common allergic reactions

What should you tell your doctor before starting Nutropin therapy?

  • If you take cyclosporine, hormone replacement therapy, insulin or other diabetes medications, drugs containing steroids, or drugs for seizures. These medications may need to be adjusted during Nutropin therapy
  • If you have preexisting tumors or growth hormone deficiency caused by abnormal tissue in the brain. If so, you should be watched closely for the worsening or return of this condition. If you had cancer as a child, an increased risk of a new tumor, particularly certain brain tumors, has been reported in patients taking Nutropin therapy
  • If you have diabetes, risk factors for diabetes, or impaired glucose tolerance. If so, your doctor should monitor your blood sugar closely during Nutropin therapy. New cases of type 2 diabetes have been reported in patients taking Nutropin therapy
  • If you have hypopituitarism (an inability of the pituitary gland to produce sufficient hormones) and are on standard hormone replacement therapy. In that case, your doctor should monitor your hormone replacement therapy closely while you are taking Nutropin therapy
  • If you are pregnant, nursing, or plan to become pregnant. It is not known whether Nutropin is excreted in human milk. Nutropin therapy should be used during pregnancy only when clearly needed

While taking Nutropin, contact your doctor immediately if you experience:

  • Changes in vision, a bad headache, or nausea with or without vomiting. This may be a sign of increased pressure in the brain
  • A limp or have hip or knee pain
    • A fracture in the ball of the hip joint can occur in children who have endocrine problems and in children who have rapid growth
    • Children with growth failure due to CKD should be examined periodically for evidence of loss of bone minerals. Hip X-rays should be taken before starting Nutropin therapy in these children
  • Progression of scoliosis (curvature of the spine) that can occur in children who have rapid growth. Nutropin therapy has not been shown to increase the occurrence of this condition
  • Any allergic reaction you experience to the injection of Nutropin therapy
  • Abdominal pain. Cases of pancreatitis (inflammation of the pancreas) have been reported rarely in children and adults receiving Nutropin therapy

Other important information about Nutropin:

  • Adults may retain water during Nutropin therapy. This may be brief but may increase with higher doses of Nutropin therapy
  • Patients should have their thyroid function tested periodically during Nutropin therapy. Thyroid hormone treatment may need to be started or adjusted
  • Patients should be sure to inject Nutropin at a different recommended place on their body each time to avoid tissue breakdown. A doctor or nurse should provide injection training and supervise the first injection
  • The use of Nutropin therapy has not been studied in patients over 65 years of age. Elderly patients may be more sensitive to Nutropin therapy and may experience more side effects
  • Patients with Turner syndrome should be monitored closely by a doctor for ear infections and cardiovascular problems during Nutropin therapy
  • Nutropin therapy may affect the body's ability to process two hormones, cortisol and cortisone, which can lead to a condition called hypoadrenalism (underactivity of the adrenal gland). In that case, glucocorticoid replacement therapy may need to be prescribed

What are common possible side effects of Nutropin therapy?

Common side effects reported in adults and children taking Nutropin therapy include injection site reactions. Additional common side effects in adults include swelling, joint pain, and carpal tunnel syndrome.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How should you store Nutropin?

Nutropin must be kept refrigerated (36° to 46°F [2° to 8°C]). Do not freeze. Cartridges and NuSpin pens must be used within 28 days of initial use. Throw away any unused Nutropin after 28 days of initial use. Before giving an injection, check the manufacturer's expiration date on the cartridge or pen. Do not use if it has expired. Do not inject medication if the solution is cloudy.

Your doctor is your primary source of information about your therapy.

Please see the full Prescribing Information for Nutropin AQ, available from your pharmacy and at www.nutropin.com, for more about Nutropin and safety.

Questions? Call the Nurse Hotline at 1-866-NUTROPIN (1-866-688-7674).

Please see additional Important Safety Information below.

View Indications and Safety Information

WHO IS NUTROPIN THERAPY FOR?

Nutropin AQ [somatropin (rDNA origin) injection] is human growth hormone that is available by prescription only in a disposable pen called NuSpin.

Doctors prescribe Nutropin therapy for children and teenagers who are short or growing slowly because they:

  • Do not make enough growth hormone on their own
  • Have idiopathic short stature, which means they are shorter than 98.8% of other children of the same age and sex; are growing at a rate not likely to allow them to reach normal adult height; and no other cause of short stature can be found
  • Have Turner syndrome
  • Have chronic kidney disease (CKD) up to the time of kidney transplant

Doctors prescribe Nutropin therapy for adults who have growth hormone deficiency that began either in:

  • Adulthood as a result of pituitary disease, diseases of the hypothalamus, surgery, radiation therapy, or trauma; or
  • Childhood. Patients treated for growth hormone deficiency in childhood, whose bones have stopped growing, should be reevaluated to see if they need to continue with growth hormone therapy

Your doctor will test to see if growth hormone is right for you.

IMPORTANT SAFETY INFORMATION

Nutropin therapy and your safety:

Please read this important safety information carefully. Then, if you have any questions, talk with your doctor.

NUTROPIN THERAPY IS NOT FOR:

  • Patients having serious complications after undergoing open heart surgery, abdominal surgery, serious injuries involving many body systems, or life-threatening breathing problems. Deaths have been reported in such cases
  • Children who have Prader-Willi syndrome (PWS) and are very overweight or have a history of severe breathing problems. Deaths have been reported in children with PWS who are very overweight, have a history of blocked upper airways, sleep apnea (pauses in breathing during sleeping), or other severe breathing problems
  • Patients who have active cancer. Because growth hormone deficiency can be an early sign of some tumors in the brain or pituitary gland, the presence of these types of tumors should be ruled out by your doctor before you start Nutropin therapy
  • Adults or children with certain types of eye disease caused by diabetes
  • Children and teenagers whose bones have finished growing
  • Patients who are allergic to somatropin, the active ingredient in Nutropin therapy. Reactions at the injection site are the most common allergic reactions

What should you tell your doctor before starting Nutropin therapy?

  • If you take cyclosporine, hormone replacement therapy, insulin or other diabetes medications, drugs containing steroids, or drugs for seizures. These medications may need to be adjusted during Nutropin therapy
  • If you have preexisting tumors or growth hormone deficiency caused by abnormal tissue in the brain. If so, you should be watched closely for the worsening or return of this condition. If you had cancer as a child, an increased risk of a new tumor, particularly certain brain tumors, has been reported in patients taking Nutropin therapy
  • If you have diabetes, risk factors for diabetes, or impaired glucose tolerance. If so, your doctor should monitor your blood sugar closely during Nutropin therapy. New cases of type 2 diabetes have been reported in patients taking Nutropin therapy
  • If you have hypopituitarism (an inability of the pituitary gland to produce sufficient hormones) and are on standard hormone replacement therapy. In that case, your doctor should monitor your hormone replacement therapy closely while you are taking Nutropin therapy
  • If you are pregnant, nursing, or plan to become pregnant. It is not known whether Nutropin is excreted in human milk. Nutropin therapy should be used during pregnancy only when clearly needed

While taking Nutropin, contact your doctor immediately if you experience:

  • Changes in vision, a bad headache, or nausea with or without vomiting. This may be a sign of increased pressure in the brain
  • A limp or have hip or knee pain
    • A fracture in the ball of the hip joint can occur in children who have endocrine problems and in children who have rapid growth
    • Children with growth failure due to CKD should be examined periodically for evidence of loss of bone minerals. Hip X-rays should be taken before starting Nutropin therapy in these children
  • Progression of scoliosis (curvature of the spine) that can occur in children who have rapid growth. Nutropin therapy has not been shown to increase the occurrence of this condition
  • Any allergic reaction you experience to the injection of Nutropin therapy
  • Abdominal pain. Cases of pancreatitis (inflammation of the pancreas) have been reported rarely in children and adults receiving Nutropin therapy

Other important information about Nutropin:

  • Adults may retain water during Nutropin therapy. This may be brief but may increase with higher doses of Nutropin therapy
  • Patients should have their thyroid function tested periodically during Nutropin therapy. Thyroid hormone treatment may need to be started or adjusted
  • Patients should be sure to inject Nutropin at a different recommended place on their body each time to avoid tissue breakdown. A doctor or nurse should provide injection training and supervise the first injection
  • The use of Nutropin therapy has not been studied in patients over 65 years of age. Elderly patients may be more sensitive to Nutropin therapy and may experience more side effects
  • Patients with Turner syndrome should be monitored closely by a doctor for ear infections and cardiovascular problems during Nutropin therapy
  • Nutropin therapy may affect the body's ability to process two hormones, cortisol and cortisone, which can lead to a condition called hypoadrenalism (underactivity of the adrenal gland). In that case, glucocorticoid replacement therapy may need to be prescribed

What are common possible side effects of Nutropin therapy?

Common side effects reported in adults and children taking Nutropin therapy include injection site reactions. Additional common side effects in adults include swelling, joint pain, and carpal tunnel syndrome.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How should you store Nutropin?

Nutropin must be kept refrigerated (36° to 46°F [2° to 8°C]). Do not freeze. Cartridges and NuSpin pens must be used within 28 days of initial use. Throw away any unused Nutropin after 28 days of initial use. Before giving an injection, check the manufacturer's expiration date on the cartridge or pen. Do not use if it has expired. Do not inject medication if the solution is cloudy.

Your doctor is your primary source of information about your therapy.

Please see the full Prescribing Information for Nutropin AQ, available from your pharmacy and at www.nutropin.com, for more about Nutropin and safety.

Questions? Call the Nurse Hotline at 1-866-NUTROPIN (1-866-688-7674).

Please see additional Important Safety Information below.

Scroll down to view complete indications and safety information

Close