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Prescribing Information

Nutropin’s 25 years of experience in growth hormone therapy

Scroll through the timeline to learn more about Nutropin

  • 1985: Genentech introduces Protropin® (somatrem for injection) for the long-term treatment of children and teenagers with growth failure who do not make enough growth hormone on their own. Protropin ceased production in 2004 as demand shifted for Nutropin® [somatropin (rDNA origin) for injection] products.
  • 1985: Genentech launches the National Cooperative Growth Study (NCGS), a 25-year study of 65,000 patients intended to further the science behind GH therapy. Initiated as a safety surveillance for the FDA, the study later became a source of scientific data.
  • 1993: Genentech launches Nutropin [somatropin (rDNA origin) for injection] for the treatment of  children and teenagers with growth failure who have chronic renal insufficiency—a slow loss of kidney function—and have not had a transplant.
  • 1994: Nutropin is approved for the long-term treatment of children and teenagers with growth failure who do not make enough growth hormone on their own.
  • 1995: Genentech introduces Nutropin AQ® [somatropin (rDNA origin) injection], the first liquid formulation for growth failure due to CRI—a slow loss of kidney function—and have not had a transplant and pediatric growth hormone deficiency (PGHD) for children and teenagers with growth failure who do not make enough growth hormone on their own.
  • 1996: Nutropin is approved for the long-term treatment of short stature in girls who have Turner syndrome.
  • 1997: Nutropin AQ and Nutropin are approved to treat adult growth hormone deficiency (AGHD) that started either in childhood or as an adult due to brain surgery, radiation therapy, trauma, or diseases of the pituitary gland or the hypothalamus.
  • 1997: Nutropin AQ receives approval for the long-term treatment of short stature in girls who have Turner syndrome.
  • 1997: Genentech launches the Single Point of Contact (SPOC) to help GH patients deal with insurance issues (now called Nutropin® Access Solutions™).
  • 2000: Genentech receives FDA approval to include data in the prescribing information that demonstrate improvement in height in pubertal patients treated with higher doses (0.7 mg/kg/week).
  • 2002: Genentech introduces the Nutropin AQ Pen, with 10 mg of Nutropin AQ.
  • 2005: Nutropin AQ® and Nutropin® are approved for long-term treatment of children and teenagers who are not likely to grow to their potential adult height, as determined by a doctor, and whose bones are still able to grow (idiopathic short stature).
  • 2005: Genentech receives FDA approval to include data in the prescribing information that demonstrate reduction of visceral adipose tissue (VAT) in adults with both adult onset and childhood onset GHD. Doctors prescribe Nutropin for adults who have growth hormone deficiency that started either in childhood or as an adult due to brain surgery, radiation therapy, trauma, or diseases of the pituitary gland or the hypothalamus.
  • 2008: Nutropin AQ Pen 20, with 20 mg Nutropin AQ, available by prescription.
  • 2008: Nutropin AQ® NuSpin™ receives FDA approval.
  • 2010: Nutropin AQ NuSpin™  5, 10, and 20 mg pens are available by prescription.

Nutropin AQ® [somatropin (rDNA origin) injection] and Nutropin® [somatropin (rDNA origin) for injection]

Three reasons:
Proven track record, comprehensive support, dependable dose delivery.

There are many reasons to consider Nutropin for you or your child’s growth hormone (GH) therapy. Here are just 3:

1: Genentech, the maker of Nutropin, has more than 25 years of experience. We were the first to introduce recombinant GH (growth hormone) therapy. We’ve worked hard to develop innovative products, services, and support to help make your experience with Nutropin more successful.

2: We’re here for you. With an entire team, working with insurance plans to help get you access to—and reimbursement for—your treatment. Once you and your doctor decide Nutropin is right for you, a dedicated Case Manager and Nurse Hotline will be available to help you through your questions. Address concerns. Solve problems.

When you or your doctor’s office calls Nutropin GPS™, we will connect you with one of our dedicated case managers whose only job is to work with you to try to get the help you need to cover the cost of your medicine. We can try to help you with issues that include:

To learn more about how we may be able to help you or a loved one, call 1-866-NUTROPIN (1-866-688-7674) and speak live with one of our case managers.

3: The innovative Nutropin AQ® NuSpin™ pen delivers liquid GH—Nutropin AQ® [somatropin (rDNA origin) injection]—from a prefilled, automatic pen. NuSpin helps make sure you deliver the full dose each time, confidently and accurately—because every dose of Nutropin matters.

Need more reasons?

Learn more about Nutropin growth hormone devices

WHO IS NUTROPIN FOR?

Nutropin® [somatropin (rDNA origin) for injection] and Nutropin AQ® [somatropin (rDNA origin) injection] are human growth hormone, available by prescription only.

Doctors prescribe Nutropin for children and teenagers with growth failure who:

  • Do not make enough growth hormone on their own
  • Have chronic renal insufficiency—a slow loss of kidney function—and have not had a transplant
  • Have Turner syndrome
  • Are not likely to grow to their potential adult height, as determined by a doctor, and whose bones are still able to grow

Doctors prescribe Nutropin for adults who:

  • Have growth hormone deficiency that started either in childhood or as an adult due to brain surgery, radiation therapy, trauma, or diseases of the pituitary gland or the hypothalamus

Your doctor will test to see if growth hormone is right for you.

IMPORTANT SAFETY INFORMATION

Nutropin and your safety:
Please read this important safety information carefully. Then, if you have any questions, talk with your doctor.

Nutropin is NOT for:

If any of these apply, talk to your doctor before you start taking Nutropin.

If you are about to start taking Nutropin, or are already taking it, be sure to tell the doctor who prescribed it:

What are the possible side effects of Nutropin?
You may experience discomfort, soreness, or redness where Nutropin is injected.

Contact your doctor immediately if you experience:

Be sure to inject Nutropin at a different recommended place on your body each time. Your doctor or nurse should supervise the first injection and provide training and instruction.

Your doctor is your primary source of information about your treatment.

Please see the full Prescribing Information for Nutropin and Nutropin AQ, available from your pharmacy and at www.nutropin.com, for more about Nutropin and safety.

Questions? Call the Nurse Hotline at 1-866-NUTROPIN (1-866-688-7674).

The content available from this website is for informational purposes only. Individual results may vary. You may report side effects to the FDA at 1-800-FDA-1088 or to Genentech Drug Safety/Adverse Events at 1-888-835-2555.

Nutropin and Nutropin AQ are registered trademarks; and NuSpin, growingopportunity, and Nutropin GPS are trademarks of Genentech Inc.

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Nutropin: Possible Side Effects

Always put your safety first: understand the possible side effects of Nutropin

Important Safety Information

WHO IS NUTROPIN FOR?

Nutropin® [somatropin (rDNA origin) for injection] and Nutropin AQ® [somatropin (rDNA origin) injection] are human growth hormone, available by prescription only.

Doctors prescribe Nutropin for children and teenagers with growth failure who:

  • Do not make enough growth hormone on their own
  • Have chronic renal insufficiency—a slow loss of kidney function—and have not had a transplant
  • Have Turner syndrome
  • Are not likely to grow to their potential adult height, as determined by a doctor, and whose bones are still able to grow

Doctors prescribe Nutropin for adults who:

  • Have growth hormone deficiency that started either in childhood or as an adult due to brain surgery, radiation therapy, trauma, or diseases of the pituitary gland or the hypothalamus

Your doctor will test to see if growth hormone is right for you.

IMPORTANT SAFETY INFORMATION

Nutropin and your safety:
Please read this important safety information carefully. Then, if you have any questions, talk with your doctor.

Nutropin is NOT for:

  • Children and teenagers whose bones have finished growing
  • Patients who have certain types of eye disease caused by diabetes
  • Patients who have active cancer or any brain tumors
  • Patients who are critically ill after open heart surgery or abdominal (stomach) surgery, are severely hurt, or have severe breathing problems
  • Children and teenagers who have Prader-Willi syndrome and are very overweight or have trouble breathing
  • Patients with a known sensitivity to benzyl alcohol, an ingredient in the liquid used to mix Nutropin Injection. Sterile water should be used when mixing Nutropin for newborns.

If any of these apply, talk to your doctor before you start taking Nutropin.

If you are about to start taking Nutropin, or are already taking it, be sure to tell the doctor who prescribed it:

  • About ALL of the medications you are taking, including supplements
  • If you have or develop a brain tumor
  • If you are given any new medication, especially glucocorticoid steroids like hydrocortisone or prednisone
  • If you are pregnant or if you become pregnant
  • About ANY other condition or illness you have or develop

What are the possible side effects of Nutropin?
You may experience discomfort, soreness, or redness where Nutropin is injected.

Contact your doctor immediately if you experience:

  • Ongoing injection site discomfort
  • Curvature of the spine (scoliosis)
  • Joint pain
  • Puffy hands and/or feet (caused by fluid retention)
  • Changes in vision, a bad headache, or nausea with or without vomiting
  • Hip or knee pain
  • A need to limp when you walk
  • Pain in wrist (carpal tunnel)
  • Allergic reaction

Be sure to inject Nutropin at a different recommended place on your body each time. Your doctor or nurse should supervise the first injection and provide training and instruction.

Your doctor is your primary source of information about your treatment.

Please see the full Prescribing Information for Nutropin and Nutropin AQ, available from your pharmacy and at www.nutropin.com, for more about Nutropin and safety.

Questions? Call the Nurse Hotline at 1-866-NUTROPIN (1-866-688-7674).

View indication and safety information

WHO IS NUTROPIN FOR?

Nutropin® [somatropin (rDNA origin) for injection] and Nutropin AQ® [somatropin (rDNA origin) injection] are human growth hormone, available by prescription only.

Doctors prescribe Nutropin for children and teenagers with growth failure who:

  • Do not make enough growth hormone on their own
  • Have chronic renal insufficiency—a slow loss of kidney function—and have not had a transplant
  • Have Turner syndrome
  • Are not likely to grow to their potential adult height, as determined by a doctor, and whose bones are still able to grow

Doctors prescribe Nutropin for adults who:

  • Have growth hormone deficiency that started either in childhood or as an adult due to brain surgery, radiation therapy, trauma, or diseases of the pituitary gland or the hypothalamus

Your doctor will test to see if growth hormone is right for you.

IMPORTANT SAFETY INFORMATION

Nutropin and your safety:
Please read this important safety information carefully. Then, if you have any questions, talk with your doctor.

Nutropin is NOT for:

  • Children and teenagers whose bones have finished growing
  • Patients who have certain types of eye disease caused by diabetes
  • Patients who have active cancer or any brain tumors
  • Patients who are critically ill after open heart surgery or abdominal (stomach) surgery, are severely hurt, or have severe breathing problems
  • Children and teenagers who have Prader-Willi syndrome and are very overweight or have trouble breathing
  • Patients with a known sensitivity to benzyl alcohol, an ingredient in the liquid used to mix Nutropin Injection. Sterile water should be used when mixing Nutropin for newborns.

If any of these apply, talk to your doctor before you start taking Nutropin.

If you are about to start taking Nutropin, or are already taking it, be sure to tell the doctor who prescribed it:

  • About ALL of the medications you are taking, including supplements
  • If you have or develop a brain tumor
  • If you are given any new medication, especially glucocorticoid steroids like hydrocortisone or prednisone
  • If you are pregnant or if you become pregnant
  • About ANY other condition or illness you have or develop

What are the possible side effects of Nutropin?
You may experience discomfort, soreness, or redness where Nutropin is injected.

Contact your doctor immediately if you experience:

  • Ongoing injection site discomfort
  • Curvature of the spine (scoliosis)
  • Joint pain
  • Puffy hands and/or feet (caused by fluid retention)
  • Changes in vision, a bad headache, or nausea with or without vomiting
  • Hip or knee pain
  • A need to limp when you walk
  • Pain in wrist (carpal tunnel)
  • Allergic reaction

Be sure to inject Nutropin at a different recommended place on your body each time. Your doctor or nurse should supervise the first injection and provide training and instruction.

Your doctor is your primary source of information about your treatment.

Please see the full Prescribing Information for Nutropin and Nutropin AQ, available from your pharmacy and at www.nutropin.com, for more about Nutropin and safety.

Questions? Call the Nurse Hotline at 1-866-NUTROPIN (1-866-688-7674).

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